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Access comprehensive datasets for Polycomb regulatory targets and literature mining results

Polycomb Regulatory Targets

Comprehensive datasets of Polycomb group protein regulatory targets across human and mouse species

This collection encompasses Polycomb group protein regulatory targets identified across normal and disease states in human and mouse models. Each dataset is available in two confidence levels: comprehensive (all targets) and high-confidence (stringently filtered targets).
Dataset Species Condition Confidence Level File Size Download
Human Normal All Homo sapiens Normal Comprehensive 35.5 MB Download Excel
Human Normal High Confidence Homo sapiens Normal High Confidence 3.4 MB Download Excel
Human Disease All Homo sapiens Disease Comprehensive 42.1 MB Download Excel
Human Disease High Confidence Homo sapiens Disease High Confidence 3.9 MB Download Excel
Mouse Normal All Mus musculus Normal Comprehensive 49.4 MB Download Excel
Mouse Normal High Confidence Mus musculus Normal High Confidence 4.5 MB Download Excel
Mouse Disease All Mus musculus Disease Comprehensive 15.3 MB Download Excel
Mouse Disease High Confidence Mus musculus Disease High Confidence 1.4 MB Download Excel

Disease Related Targets

Polycomb targets associated with disease states through computational analysis

This collection encompasses Polycomb group protein targets specifically associated with disease mechanisms through computational analysis. The dataset includes three distinct categories of disease-related targets with comprehensive tissue distribution and PTS score analysis, derived from systematic analysis of high-confidence ChIP-seq and RNA-seq data.
Data Content Overview
  • Sheet 1 - Overview: Summary statistics and analysis methodology
  • Sheet 2 - Acquired Drivers: Cross-species conserved disease-specific genes (normal states excluded)
  • Sheet 3 - Common Targets: Cross-species conserved genes with both normal and disease states within same tissues
  • Sheet 4 - Perturbed Biomarkers: Targets with significant and directionally consistent PTS changes
Target Category File Size Download
Disease Related Targets 453 KB Download Excel

Literature Mining Results

Systematic text mining analysis of Polycomb-related research from peer-reviewed literature

This dataset contains systematically extracted information from peer-reviewed scientific literature regarding Polycomb group proteins, their regulatory relationships, and associated biological processes.
Dataset Description File Size Download
Literature Mining Results Comprehensive text mining analysis including gene identifiers, regulatory relationships, PubMed citations, and experimental evidence 768 KB Download Excel
Data Usage Information

All datasets are provided in Microsoft Excel format (.xlsx) and are compatible with Excel, LibreOffice Calc, and other spreadsheet applications. Due to the comprehensive nature of these datasets, download times may vary depending on network conditions. Please cite the PRIME database appropriately when using these data in scientific publications.